Postnatal neurogenesis in the human brain

Recently, a lot of data has been gathered which demonstrates neurogenesis in the brain adult humans. In genetics, findings have obtained that not only prove, but also elucidate molecular mechanisms neurogenesis. some publications, however, morphology disputes neuronal renewal adulthood. Therefore, this review presents modern achievements epigenetics, morphology, and physiology, confirm characterize postnatal detail. We suggest introduction genetic technologies into morphological studies will be starting point for integration these areas, complementing each other targeted therapy clinical practice. Numerous evidence presence humans using bromodeoxyuridine, carbon isotope 14C, 3H-thymidine, comparative analyses experimental from animals. Neuronal stem cells, represented by radial glia present subventricular subgranular zones human brain, are morphologically similar to neuroepithelial cells. They express marker proteins astrocytes, suggests proliferation neuroglia found adults can indicate regeneration neurons. To prove this, further required, with exact identification newly-formed specific markers, epigenetics. The methods facilitate accurate determination classification cells subpopulation study effects various agents on neurons brain.